What is NMN?
NMN is the abbreviation of “Nicotinamide Mononucleotide”, the Chinese name is “β-nicotinamide mononucleotide”, the main function is to synthesize NAD+
, it will participate in large and small metabolic reactions,
Helping the body convert food into energy, is a very important nutrient.NAD+ will be lost at a fault rate with age, and cannot be absorbed through diet, and
NMN is the most direct precursor for the synthesis of NAD+, so supplement NMN to increase the concentration of NAD+ in the body , is very important for
regulating physiological functions, maintaining beauty, youth and beauty, and maintaining health.
Why should you supplement with NMN?
NMN Function 1: Regulating Physiological Function
Eight
Nobel Prize winners have conducted research on the efficacy of NMN.
Experiments have confirmed that NMN has biological activity and will participate in more than 500 physiological reactions in the human body, so sufficient NMN supplementation Helps maintain normal physiological functions.
NMN effect 2: beautify the skin and maintain youth
NMN can
activate the expression of youth factors,
help maintain youthful beauty, and in health food, it often forms a compound with glutathione (GSH) and vitamin C. Through the compound Multiply the antioxidant capacity to help fight against the damage of risk factors.
NMN effect 3: promote metabolism
After NMN generates NAD+ in the human body, NAD+ will participate in various energy metabolism reactions, generate energy needed for activities, and help maintain normal metabolism.
Are there any side effects of NMN?
NMN is an inherent ingredient in the human body, and also exists in natural food, so
just choose NMN from natural sources and supplement it in an appropriate amount, basically there will be no side effects. At present, no obvious side effects have been found in clinical animal and human experiments, so it can be eaten with peace of mind.NMN also exists in natural foods, such as edamame, avocado, broccoli, tomato, mushroom, etc. can all contain NMN, so adjusting the diet can also increase the intake of NMN. But
The NMN content in food is not high. Taking tomatoes as an example, each kilogram contains 3mg of NMN, and at least 600 tablets a day can meet the daily NMN requirement of the human body (250mg).
#source: Irie J, Inagaki E, Fujita M, et al. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocr J. 2020;67(2):153-160. doi:10.1507/endocrj.EJ19-0313
*source: Mills K ,Yoshida S, Stein L et al. (2016) .Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice[J]. Cell Metabolism, 24(6):795-806. (This is the research result in animal model)
^source: Heer CD, Sanderson DJ, Voth LS, et al. Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. J Biol Chem. 2020;295(52):17986-17996. doi:10.1074/jbc.RA120.015138